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Scientific publication journal
The first step of semisolid drugs modification is a pick of appropriate base. As we plan to develop a preparation for treating of inflammatory periodontal diseases, it is necessary to take into account about requirements: base should supply a p H contiguous to the p H of the opening secretion membranes, be easily and painlessly applied to the gums, be uniformly distributed, have a featherlike texture. As the optimal basis should be well applied to the oral mucosa, does not spread and possess medium fluidity, for more studies, we have chosen a carbomer with strengthening of 1%.